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Science

Abstract 1. A functional description of immunity 2. Activation of innate immunity by microbial products 3. The history of beta-1,3/1,6-glucans 4. Chemistry, properties and manufacture of glucans and beta-1,3/1,6-glucans 5. Mode of action and biological effects 6. Safety 7. Selected pre-clinical "proof-of-concept" studies 8. Description of selected clinical trials 9. Skepticism to beta-1,3/1,6-glucan 10. Conclusion References